Low-dose aripiprazole for refractory burning mouth syndrome
نویسندگان
چکیده
We report a case of refractory burning mouth syndrome (BMS) ameliorated with low dose of aripiprazole. The patient was a 66-year-old female who had suffered from chronic burning pain in her tongue for 13 months. No abnormality associated with the burning sensation was detected in the laboratory tests and the oral findings. Considering the clinical feature and the history together, we diagnosed the burning sensation as BMS. The BMS pain was decreased by aripiprazole (powder) 1.0 mg/d, though no other antidepressants had satisfying pain relief. It could be supposed that the efficacy of aripiprazole is caused by dopamine stabilization in this case, and BMS might have a subtype that is reactive to aripiprazole. Further studies are needed to confirm the efficacy of aripiprazole for BMS.
منابع مشابه
Low-Dose Aripiprazole Augmentation in Amitriptyline-Resistant Burning Mouth Syndrome: Results from Two Cases
Despite the efficacy of antidepressants such as amitriptyline for alleviating burning mouth syndrome (BMS) [1,2], BMS may persist after antidepressant monotherapy. However, recent case reports have shown that aripiprazole (APZ) augmentation can reduce chronic pain resistant to other treatments [3]. Herein, we present two cases in which patients with BMS responded well to a very low dose of APZ ...
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